Advancing Drug Discovery Through AI-Powered Solutions

Kinase Knowledgebase (KKB)

Currently the Kinase Knowledgebase Q4 2025 Release includes the following data:

• Journal articles and patents: 10,270
• Number of Biological Activity Data Points: 2,949,253
• Number of unique kinase molecules with annotated assay data: 447,140
• Number of all unique kinase molecules from patents and articles (with or without bio-activity data): 791,020
• Number of unique kinase targets with assay data: 576
• Number of annotated assay protocols: 100,714

Oncology Knowledgebase (OKB)

Currently the Oncology Knowledgebase Q2 2023 Release includes the following data:

• Journal articles and patents: 977
• Number of Biological Activity Data Points: 146,206
• Number of molecules from patents and articles: 66,198
• Number of unique oncology targets with assay data: 1,158
• Number of annotated assay protocols: 5,614
• Number of disease models: 137

Target Informatics Platform (TIP™)

The Target Informatics Platform's content grows weekly with more than 200K high resolution protein structures, ~1.2M annotated co-complex sites, and an additional ~875K predicted sites. TIP contains more than 710K protein chains representing every major drug target family.