Eidogen-Sertanty Releases Major Database Upgrades

San Diego, CA (November 9, 2007) –- Eidogen-Sertanty, Inc., a computational drug discovery solutions provider, today announced the release of major upgrades to its onlineTIP knowledgebase (onlineTIP) and its Kinase Knowledgebase (KKB).

The onlineTIP upgrade includes data from the recent Protein Databank (PDB) remediation project as well as newly released, highly significant PDB structural information. As a result of the PDB remediation project, many previously inconsistent PDB formatted files became accessible to TIP's StructFast, StructSorter, SiteSeeker, and SiteSorter algorithms. Combined with newly released protein structure coordinates, including the recently released "Structure of an Engineered Human {beta}2-Adrenergic G Protein Coupled Receptor (Science, 2007)," the scope of protein structures, models, binding-sites, and their respective correlations increased significantly within onlineTIP

Along with the enhanced coverage and scope of data, onlineTIP content now resides in relational database form. TIP content in relational form means easier access, more facile association with other content, and more efficient integration with other technologies.

Concomitant with the onlineTIP upgrade is another quarterly release of the Kinase Knowledgebase (KKB), which now contains over 300,000 SAR data points curated from over 3700 journal articles and patents. The KKB is available in export form accessible by Accelrys-Scitegic's Pipeline Pilot® and in relational database format supporting Symyx® ISIS and Symyx® Iscentris®, Accelrys-Accord and Daylight-DayCart® relational database cartridge technologies.

"We are very excited about these two important database releases," said Steve Muskal, CEO of Eidogen-Sertanty. "Providing all of our key content offerings in relational database form now affords our clients the opportunity to integrate, search, and mine the cross-sectional wealth of information found between the often disconnected worlds of target- and ligand-based information."

Contact Information:
Steve Muskal
760-729-0211
pr@eidogen-sertanty.com

About Eidogen-Sertanty, Inc.
Eidogen-Sertanty, formed in March 2005 from the merger of Eidogen and Sertanty, is a privately held company providing pioneering knowledge-driven discovery solutions to biotechnology and pharmaceutical organizations.  Eidogen-Sertanty’s unique and powerful suite of software, databases, and drug discovery services enable customers and collaborators to apply a knowledge-driven discovery approach to a variety of workflows and processes, including target selection and prioritization, library building and compound prioritization, and lead design and optimization.  To find out more about Eidogen-Sertanty and their products and services please visit www.eidogen-sertanty.com.

About Symyx
Symyx Technologies, Inc. is the R&D execution partner to the life sciences, chemicals, energy, consumer products and electronics industries. Symyx provides electronic lab notebook and scientific decision-support software, automated lab systems (workflows) and collaborative research services to improve R&D productivity. In October 2007, Symyx acquired MDL Information Systems, Inc., a leading provider of innovative informatics software, databases and services that accelerate successful scientific R&D by improving the speed and quality of scientists' decision making. For more information about Symyx, visit http://www.symyx.com.

About Accelrys, Inc.
Accelrys has over twenty years of innovation and technology leadership in delivering software and service solutions that transform discovery and development research. A unique combination of expertise in life and materials science, informatics, and scientific operating platform technologies, lets Accelrys serve a diverse range of clients, including some of the world's leading pharmaceutical, biotechnology, chemical, and nanotechnology research organizations. Accelrys is headquartered in San Diego, California. For more information about Accelrys, visit http://www.accelrys.com.

About Daylight, CIS
Daylight provides software that delivers state-of-the art chemical information processing to individual users and enterprise systems. Daylight's revolutionary SMILESTM, SMARTS®, and SMIRKS® chemical languages are supported in all its products from tool kits to data cartridges. Superior chemistry, high performance, and open architecture have earned Daylight a reputation for excellence since 1987. Daylight Chemical Information Systems, Inc. is a privately held company with corporate offices in Aliso Viejo, CA and research offices in Santa Fe, NM and Cambridge, England. For more information about Daylight, visit http://www.daylight.com.